odmj
OncoDaily Medical Journal
ODMJ
3067-6444
OncoDaily Medical Journal
US
6050
10.69690/ODMJ-011-1122-6050
Case Reports & Case Series
Invasive Cutaneous and Ocular Candidiasis in a Child with DOCK8 Deficiency: A Case Report
Yahya
Walaa Ahmed Abdo
Ministry of Heath and Population/Yemen
dr.walaa.alkady@gmail.com
Ahmed
Tarek
Faculty of Medicine, Sohag University, Sohag, Egypt
Gaffer
Enas Nagi
Oncology Specialized Medical Centre, Ministry of Health, Cairo, Egypt
22
11
2025
ODMJ-011-1122-6050
Copyright (c) 2025 OncoDaily Medical Journal
2025
OncoDaily Medical Journal
DOCK8
DOCK8 Deficiency
Fungal keratitis
Invasive candidiasis
Ocular Candidiasis
pediatric oncology
Primary immunodeficiency
production-ready-file-url
[
Lass-Flörl C, Kanj SS, Govender NP, Thompson GR 3rd, Ostrosky-Zeichner L, Govrins MA. Invasive candidiasis. Nat Rev Dis Primers. 2024 Mar 21;10(1):20.
]
[
Pappas PG, Lionakis MS, Arendrup MC, Ostrosky-Zeichner L, Kullberg BJ. Invasive candidiasis. Nat Rev Dis Primers. 2018 May 11;4:18026.
]
[
Gonzalez-Lara MF, Ostrosky-Zeichner L. Invasive Candidiasis. Semin Respir Crit Care Med. 2020 Feb;41(1):3-12.
]
[
Mukherjee B, Raichura ND, Alam MS. Fungal infections of the orbit. Indian J Ophthalmol. 2016 May;64(5):337-45
]
[
Mezri S, et al. Case report: invasive candidiasis of the head and neck in a five-month-old infant: a case study. F1000Res. 2024;13:1232.
]
[
Douglas AP, Thursky KA, Worth LJ, Drummond E, Hogg A, Hicks RJ, Slavin MA et al. FDG PET/CT imaging in detecting and guiding management of invasive fungal infections: a retrospective comparison to conventional CT imaging. Eur J Nucl Med Mol Imaging. 2019 Jan;46(suppl 1):166–173.
]
[
Pappas PG, Kauffman CA, Andes DR, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2016 Feb 15;62(4):e1-50.
]
[
Alcaraz-Micheli L, Moon C. Fungal keratitis. American Academy of Ophthalmology EyeWiki. 2014, May
]
[
Awad R, Ghaith AA, Awad K, Mamdouh Saad M, Elmassry AA. Fungal Keratitis: Diagnosis, Management, and Recent Advances. Clin Ophthalmol. 2024 Jan 10;18:85-106.
]
[
Ollech A, et al. Treatment options for DOCK8 deficiency-related severe dermatitis. J Dermatol. 2021 May 27;48(9):1386–1393.
]
[
Gowri V, Chougule A, Gupta M, et al. Clinical, immunological and molecular findings of patients with DOCK-8 deficiency from India. Scand J Immunol. 2023 Jul;98(1):e13276.
]
[
Freeman AF, Gonzalez CE, Yates B et al. Hematopoietic cell transplantation for DOCK8 deficiency: results from a prospective clinical trial. J Allergy Clin Immunol. 2025 Jan;155(1):176-187.
]