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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">odmj</journal-id>
      <journal-title-group>
        <journal-title xml:lang="en">OncoDaily Medical Journal</journal-title>
        <abbrev-journal-title abbrev-type="publisher">ODMJ</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">3067-6444</issn>
      <publisher>
        <publisher-name>OncoDaily Medical Journal</publisher-name>
        <publisher-loc>
          <country>US</country>
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    <article-meta>
      <article-id pub-id-type="publisher-id">8087</article-id>
      <article-id pub-id-type="doi">10.69690/ODMJ-002-0926-8087</article-id>
      <article-categories>
        <subj-group xml:lang="en" subj-group-type="heading">
          <subject>Reviews</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title xml:lang="en">Risk of Atrial Fibrillation in Breast Cancer Patients Treated with Radiotherapy: A Scoping Review</article-title>
      </title-group>
      <contrib-group content-type="author">
        <contrib contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Georgiou</surname>
            <given-names>Christina</given-names>
          </name>
          <aff xml:lang="en">Research Department, German Oncology Center; Cyprus</aff>
          <email>christina27.georgiou@gmail.com</email>
        </contrib>
        <contrib contrib-type="author">
          <name name-style="western">
            <surname>Cloconi</surname>
            <given-names>Constantina</given-names>
          </name>
          <aff xml:lang="en">Research Department, German Oncology Center</aff>
        </contrib>
        <contrib contrib-type="author">
          <name name-style="western">
            <surname>Kosmidis</surname>
            <given-names>Georgios</given-names>
          </name>
          <aff xml:lang="en">Research Department, German Oncology Center</aff>
        </contrib>
        <contrib contrib-type="author">
          <name name-style="western">
            <surname>Christodoulou</surname>
            <given-names>Artemis</given-names>
          </name>
          <aff xml:lang="en">Research Department, German Oncology Center</aff>
        </contrib>
        <contrib contrib-type="author">
          <name name-style="western">
            <surname>Ferentinos</surname>
            <given-names>Konstantinos</given-names>
          </name>
          <aff xml:lang="en">Research Department, German Oncology Center</aff>
        </contrib>
      </contrib-group>
      <pub-date date-type="pub" publication-format="electronic">
        <day>30</day>
        <month>09</month>
        <year>2026</year>
      </pub-date>
      <pub-history>
        <event event-type="received">
          <event-desc>Received: <date date-type="received" iso-8601-date="2026-03-13T00:00:00+00:00"><day>13</day><month>03</month><year>2026</year></date></event-desc>
        </event>
        <event event-type="accepted">
          <event-desc>Accepted: <date date-type="accepted" iso-8601-date="2026-08-22T00:00:00+00:00"><day>22</day><month>08</month><year>2026</year></date></event-desc>
        </event>
      </pub-history>
      <elocation-id>ODMJ-002-0926-8087</elocation-id>
      <permissions>
        <copyright-statement>Copyright (c) 2026 OncoDaily Medical Journal</copyright-statement>
        <copyright-year>2026</copyright-year>
        <copyright-holder>OncoDaily Medical Journal</copyright-holder>
      </permissions>
      <self-uri xlink:href="https://oncodailyjournal.com/10.69690/odmj-002-0926-8087/"/>
      <kwd-group xml:lang="en">
        <kwd>arrhythmias</kwd>
        <kwd>atrial fibrillation</kwd>
        <kwd>Breast Cancer</kwd>
        <kwd>breast neoplasm</kwd>
        <kwd>malignancy</kwd>
        <kwd>Radiotherapy</kwd>
        <kwd>tumour</kwd>
      </kwd-group>
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            <ext-link ext-link-type="uri" xlink:href="https://oncodailyjournal.com/pub/uploads/2026/09/Risk-of-Atrial-Fibrillation-in-Breast-Cancer.pdf"/>
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    </article-meta>
  </front>
  <body/>
  <back>
    <ref-list>
      <ref id="R1">
        <mixed-citation>World Health Organization. Breast cancer [Internet]. Geneva: World Health Organization; 2026 Jul 3 [cited 2026 Sep 3]. Available from: https://www.who.int/news-room/fact-sheets/detail/breast-cancer</mixed-citation>
      </ref>
      <ref id="R2">
        <mixed-citation>Wang H, Wei J, Zheng Q, et al. Radiation-induced heart disease: a review of classification, mechanism and prevention. Int J Biol Sci. 2019 Aug 8;15(10):2128-38. doi:10.7150/ijbs.35460.</mixed-citation>
      </ref>
      <ref id="R3">
        <mixed-citation>Li X, Wu Y, Wang Q, et al. Radiation-induced cardiac substructure damage and dose constraints: a review. Radiat Oncol. 2025 Jun 5;20(1):94. doi:10.1186/s13014-025-02668-x.</mixed-citation>
      </ref>
      <ref id="R4">
        <mixed-citation>Chin V, Finnegan RN, Keall P, et al. Overview of cardiac toxicity from radiation therapy. J Med Imaging Radiat Oncol. 2024 Dec;68(8):987-1000. doi:10.1111/1754-9485.13757.</mixed-citation>
      </ref>
      <ref id="R5">
        <mixed-citation>Uehara M, Bekki N, Shiga T. Radiation-associated cardiovascular disease in patients with cancer: current insights from a cardio-oncologist. J Radiat Res. 2024 Sep 10;65(5):575-90. doi:10.1093/jrr/rrae068.</mixed-citation>
      </ref>
      <ref id="R6">
        <mixed-citation>Zou B, Schuster JP, Niu K, et al. Radiotherapy-induced heart disease: a review of the literature. Precis Clin Med. 2019 Dec;2(4):270-82. doi:10.1093/pcmedi/pbz025.</mixed-citation>
      </ref>
      <ref id="R7">
        <mixed-citation>Mauro E, Lucà F, Tetta C, et al. Breast cancer and atrial fibrillation. J Clin Med. 2022 Mar 4;11(5):1417. doi:10.3390/jcm11051417.</mixed-citation>
      </ref>
      <ref id="R8">
        <mixed-citation>Mauriello A, Correra A, Quagliariello V, et al. Atrial fibrillation and cancer: pathophysiological mechanism and clinical implications. J Clin Med. 2025 Aug 7;14(15):5600. doi:10.3390/jcm14155600.</mixed-citation>
      </ref>
      <ref id="R9">
        <mixed-citation>Davis NE, Prasitlumkum N, Tan NY. Atrial fibrillation and cancer—epidemiology, mechanisms, and management. J Clin Med. 2024 Dec 19;13(24):7753. doi:10.3390/jcm13247753.</mixed-citation>
      </ref>
      <ref id="R10">
        <mixed-citation>Pang Z, Ren Y, Yao Z. Interactions between atrial fibrosis and inflammation in atrial fibrillation. Front Cardiovasc Med. 2025 Jul 10;12:1578148. doi:10.3389/fcvm.2025.1578148.</mixed-citation>
      </ref>
      <ref id="R11">
        <mixed-citation>Liu Y, Chen Y, Ren Q, et al. Atrial fibrillation: from pathogenesis to novel treatment options. Mol Biomed. 2025 Dec 19;6:144. doi:10.1186/s43556-025-00393-1.</mixed-citation>
      </ref>
      <ref id="R12">
        <mixed-citation>Murg SI, Matiș L, Moldovan AF, et al. Cardiotoxicity in breast cancer: impact of clinical classifications and treatment on heart health. Cancers (Basel). 2024 Dec 23;16(24):4281. doi:10.3390/cancers16244281.</mixed-citation>
      </ref>
      <ref id="R13">
        <mixed-citation>Díaz-Gavela AA, Figueiras-Graillet L, Montero Luis Á, et al. Breast radiotherapy-related cardiotoxicity: when, how, why. Risk prevention and control strategies. Cancers (Basel). 2021 Apr 4;13(7):1712. doi:10.3390/cancers13071712.</mixed-citation>
      </ref>
      <ref id="R14">
        <mixed-citation>Arksey H, O’Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol. 2005 Feb;8(1):19-32. doi:10.1080/1364557032000119616.</mixed-citation>
      </ref>
      <ref id="R15">
        <mixed-citation>Peters MDJ, Godfrey C, McInerney P, et al. Chapter 11: scoping reviews (2020 version). In: Aromataris E, Munn Z, editors. JBI Manual for Evidence Synthesis. Adelaide: JBI; 2020. doi:10.46658/JBIMES-20-12.</mixed-citation>
      </ref>
      <ref id="R16">
        <mixed-citation>Munn Z, Peters MDJ, Stern C, et al. Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach. BMC Med Res Methodol. 2018 Nov 19;18(1):143. doi:10.1186/s12874-018-0611-x.</mixed-citation>
      </ref>
      <ref id="R17">
        <mixed-citation>Guha A, Fradley MG, Dent SF, et al. Incidence, risk factors, and mortality of atrial fibrillation in breast cancer: a SEER-Medicare analysis. Eur Heart J. 2022 Jan 21;43(4):300-12. doi:10.1093/eurheartj/ehab745.</mixed-citation>
      </ref>
      <ref id="R18">
        <mixed-citation>Jacobs JEJ, L’Hoyes W, Lauwens L, et al. Mortality and major adverse cardiac events in patients with breast cancer receiving radiotherapy: the first decade. J Am Heart Assoc. 2023 Apr 18;12(8). doi:10.1161/JAHA.122.027855.</mixed-citation>
      </ref>
      <ref id="R19">
        <mixed-citation>Mery B, Fouilloux A, Rowinski E, et al. Cardiovascular disease events within 5 years after a diagnosis of breast cancer. BMC Cancer. 2020 Apr 21;20(1):337. doi:10.1186/s12885-020-06838-w.</mixed-citation>
      </ref>
      <ref id="R20">
        <mixed-citation>Apte N, Dherange P, Mustafa U, et al. Cancer radiation therapy may be associated with atrial fibrillation. Front Cardiovasc Med. 2021 Jan 22;8:610915. doi:10.3389/fcvm.2021.610915.</mixed-citation>
      </ref>
      <ref id="R21">
        <mixed-citation>Grewal US, Patel HP, Sheth AR, et al. Impact of radiation on inpatient outcomes in patients with breast cancer and atrial fibrillation. Heart Rhythm. 2022 Jul;19(7):1210-1. doi:10.1016/j.hrthm.2022.03.014.</mixed-citation>
      </ref>
      <ref id="R22">
        <mixed-citation>Ravassa S, López B, Treibel TA, et al. Cardiac fibrosis in heart failure: focus on non-invasive diagnosis and emerging therapeutic strategies. Mol Aspects Med. 2023 Oct;93:101194. doi:10.1016/j.mam.2023.101194.</mixed-citation>
      </ref>
      <ref id="R23">
        <mixed-citation>Kong Y, Yang C, Xie L, et al. Cardiac toxicity and intervention strategies during thoracic cancer radiotherapy. Front Oncol. 2025 Aug 4;15:1638035. doi:10.3389/fonc.2025.1638035.</mixed-citation>
      </ref>
      <ref id="R24">
        <mixed-citation>Hsieh K, Hotca AE, Runnels J, et al. The effects of radiation therapy on the heart: implications for management. Chin Clin Oncol. 2024 Feb 20;13(1):10. doi:10.21037/cco-23-125.</mixed-citation>
      </ref>
      <ref id="R25">
        <mixed-citation>Desai MY, Jellis CL, Kotecha R, et al. Radiation-associated cardiac disease: a practical approach to diagnosis and management. JACC Cardiovasc Imaging. 2018;11(8):1132-49. doi:10.1016/j.jcmg.2018.04.028.</mixed-citation>
      </ref>
      <ref id="R26">
        <mixed-citation>Butler S, No H, Guo F, et al. Predictors of atrial fibrillation after thoracic radiotherapy. JACC CardioOncol. 2024;6(6):935-45. doi:10.1016/j.jaccao.2024.08.007.</mixed-citation>
      </ref>
      <ref id="R27">
        <mixed-citation>Errahmani MY, Locquet M, Spoor D, et al. Association between cardiac radiation exposure and the risk of arrhythmia in breast cancer patients treated with radiotherapy: a case-control study. Front Oncol. 2022;12:892882. doi:10.3389/fonc.2022.892882.</mixed-citation>
      </ref>
      <ref id="R28">
        <mixed-citation>Stefan MF, Herghelegiu CG, Magda SL. Accelerated atherosclerosis and cardiovascular toxicity induced by radiotherapy in breast cancer. Life (Basel). 2023;13(8):1631. doi:10.3390/life13081631.</mixed-citation>
      </ref>
      <ref id="R29">
        <mixed-citation>Jacob A, Thyagarajan B, Kumar MP, et al. Cardiovascular effects of Hodgkin’s lymphoma: a review of literature. J Cancer Res Clin Oncol. 2018;144(1):99-107. doi:10.1007/s00432-017-2560-x.</mixed-citation>
      </ref>
      <ref id="R30">
        <mixed-citation>Yang Q, Zheng J, Zhao C, et al. Association Between Inflammation and Risk of Cardiovascular Mortality in Cancer Survivors: a population-based cohort study using UK Biobank. Cardiooncology. 2026;12:8. doi:10.1186/s40959-025-00414-6.</mixed-citation>
      </ref>
      <ref id="R31">
        <mixed-citation>Bello MO, Wadid M, Malode A, et al. Atrial fibrillation in patients with breast cancer: a literature review. Cardiol Ther. 2025;14(1):1-15. doi:10.1007/s40119-024-00394-1.</mixed-citation>
      </ref>
    </ref-list>
  </back>
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